Home > Field of Cooperation > Health Research > The Predict-XDR Project: Predicting genetic markers for pre-XDR and XDR tuberculosis
The Predict-XDR Project: Predicting genetic markers for pre-XDR and XDR tuberculosis |
| Principal Investigator / Affiliation | Raul Destura (Deputy Executive Director) / Philippine Genome Center (UP System)  Philippines |
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Midori Kato-Maeda (Associate Professor) / University of California San Francisco  USA |
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Satoshi Mitarai (Professor) / Research Institute of Tuberculosis  Japan |
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| Year Adopted | 2019 |
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| General Description of the Research Project | This cooperative research project aims to identify novel markers that predict pre-extensively drug-resistant (pre-XDR) and XDR tuberculosis (TB). Genetic markers associated with fluoroquinolones (FQ) and second line injectables (SLI) resistance are incompletely characterized, contributing to the variable sensitivity of molecular assays. We will perform comparative genomic analyses to identify novel mutations and DNA-methylation patterns associated with FQ and SLI resistance. |
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Researchers
| Principal Investigator / Country of Research Team | 
Raul Destura the Philippines |
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