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Integrated application of human and pathogen genomic information for improvement of treatment outcome and control of drug-resistance in Asian tuberculosis patients |
Principal Investigator / Affiliation | Katsushi Tokunaga (Director) / National Center for Global Health and Medicine (NCGM) Japan |
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Surakameth Mahasirimongkol (Medical Doctor) / Ministry of Public Health Thailand | |
Ma. Cecilia Ama (Head) / Research Institute for Tropical Medicine Philippines | |
Rika Yuliwulandari (Dean) / YARSI University Indonesia | |
Year Adopted | 2019 |
Research Period | |
General Description of the Research Project | The integrated analysis of human and Mycobacterium tuberculosis aims to identify genomic biomarkers associated with efficacy of anti-tuberculosis (TB) treatment, risk of adverse drug reactions (ADRs), systemic exposure of anti-TB drugs, and occurrence of drug–resistance strain of M. tuberculosis. Biomarkers will be used for establishment of precision medicine for successful treatment and reduction of drug resistance in Asian TB patients. |
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Principal Investigator / Country of Research Team | Katsushi Tokunaga Japan Surakameth Mahasirimongkol Thailand Ma. Cecilia Ama the Philippines |
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