Targeting MYCN/NCYM for cancer therapy |
Principal Investigator / Affiliation | Yoshitaka Hippo (Department Head) / Chiba Cancer Center Japan |
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Tao Liu (Group Leader) / The University of New South Wales Australia | |
Edy Meiyanto (Professor) / Gadjah Mada University Indonesia | |
Year Adopted | 2021 |
Research Period | 3 years |
General Description of the Research Project | The aim of this project is to develop novel therapeutic strategies for liver cancer by targeting MYCN/NCYM. The effects of anti-cancer agents inhibiting MYCN/NCYM function, obtained either from natural resources or through chemical synthesis, will be examined using patient-derived organoid and mouse models for potential translation into clinical trials. Multi-omics will reveal the molecular mechanisms underlying the tumor suppressive effects |
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Researchers
Principal Investigator / Country of Research Team | Yoshitaka Hippo Japan Tao Liu Australia Edy Meiyanto Indonesia |
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