Home > Field of Cooperation > Health Research > Development of Innovative Antimicrobials for Combatting Multidrug-resistant Gram-negative Bacteria: An integrated multi-disciplinary approach
Development of Innovative Antimicrobials for Combatting Multidrug-resistant Gram-negative Bacteria: An integrated multi-disciplinary approach |
| Principal Investigator / Affiliation | Jian Li (Professor/Head of the Laboratory of Antimicrobial Systems Pharmacology) / Monash University  Australia |
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Qi Zhou (Associate Professor) / Purdue University  USA |
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Visanu Thamlikitkul (Professor/Director of WHO Collaborating Center for AMR Prevention and Containment) / Siriraj Hospital  Thailand |
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| Year Adopted | 2022 |
| Research Period | 3 years |
| General Description of the Research Project | This project will discover urgently needed new antibiotics for life-threatening infections caused by multidrug-resistant Gram-negative pathogens. We will integrate cutting-edge computational, cell and chemical biology and intelligent drug design to discover and evaluate novel, safer lipopeptide antibiotics (Australian team); employ innovative drug delivery technology to develop superior inhalation formulations (USA team); and conduct systematic pre-clinical studies for commercialisation of our new antibiotics (Australian and Thai teams). This collaborative project targets a significant unmet global medical need due to antibiotic resistance |
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Researchers
| Principal Investigator / Country of Research Team | 
Jian Li Australia
Qi Zhou the United States
Visanu Thamlikitkul Thailand |
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