Home > Field of Cooperation > Health Research > Deciphering the AMR and hypervirulence in Klebsiella pneumoniae infections
Deciphering the AMR and hypervirulence in Klebsiella pneumoniae infections |
| Principal Investigator / Affiliation | Yohei Doi (Professor of Medicine) / Fujita Health University  Japan |
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Christian Francisco (Research Faculty/Consultant) / University of the Philippines  Philippines |
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Janet Lee (Professor of Medicine) / Washington University  USA |
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| Year Adopted | 2022 |
| Research Period | 3 years |
| General Description of the Research Project | This tripartite cooperative research project aims to elucidate antimicrobial resistance (AMR) and hypervirulence (HV) of Klebsiella pneumoniae (KP) infections in the Philippines and Japan. The overarching hypotheses are that HV strains cause infections with distinct clinical features in the two countries, and that acquisition of AMR adversely affects patient outcome. We will address these hypotheses through prospective patient cohorts supported by microbiology, genomics and virulence studies. Furthermore, we will develop a PCR-based typing method that simultaneously identifies AMR and HV |
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Researchers
| Principal Investigator / Country of Research Team | 
Yohei Doi Japan
Christian Francisco the Philippines
Janet Lee the United States |
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